Leukotriene C4

The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)

Also Known As:

Leukotriene C; Leukotriene C-1; Leukotriene C-4; Leukotriene C1; Leukotrienes C; Leukotriene C 1; Leukotriene C 4; LTC4; Glycine, N- (S- (1- (4- carboxy- 1- hydroxybutyl)- 2,4,6,9- pentadecatetraenyl)- N- L- gamma- glutamyl- L- cysteinyl)- , (R-(R*,S*-(E,E,Z,Z)))-

Lipids: 118169
- Fatty Acids: 28212
  - Unsaturated Fatty Acids: 8458
    - Eicosanoids: 3282
      - Arachidonic Acids: 125
        Leukotrienes: 4119
        SRS-A: 188
        Leukotriene C4: 872
    - Essential Fatty Acids: 744
      - Arachidonic Acids: 125
        Leukotrienes: 4119
        SRS-A: 188
        Leukotriene C4: 872
Biological Factors: 2560
- Inflammation Mediators: 1126
  - Autacoids: 278
    - Eicosanoids: 3282
      - Leukotrienes: 4119
        SRS-A: 188
        Leukotriene C4: 872

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